Measurement Zinc and Copper concentrations in biological samples of lung cancer patients

Abstract

Blood study in the present work, atomic absorption spectroscopy was used to study the differences in the concentration of trace elements (Zn and Cu) between the serum of healthy human and lung cancer patients. Samples were collected from Ibn Marjana Hospital in Hillah Governorate. Lung cancer is one of the most common leading causes of cancer deaths worldwide. Recently, many efforts have been made to use the elemental contents in the human body to help diagnose various diseases including cancer. Therefore, this study aimed to investigate the serum contents of lung cancer patients of Zn and Cu and compare them with those of controls using atomic absorption spectroscopy. The results showed that zinc levels were statistically significant between lung cancer patients and healthy controls, with healthy subjects having a 1.832±0.741 lower level compared to lung cancer patients (1.288±0.568 µg/L) compared to lung cancer females (p = 0.002) compared to lung cancer females (p = 0.002). Meanwhile, copper levels in lung cancer were 0.059±0.034 µg/L lower than healthy females (0.071±0.048) (p = 0.238) compared to lung cancer females (p = 0.238). The mean serum levels of zinc and copper were statistically significant, while copper was not.